Low- and middle-income countries are severely affected by climate change, but evidence for guiding uptake of suitable interventions is currently limited. Dr Tukuitonga and Dr Bunker will lead a global multi-centre trial in Burkina Faso, India, Niue and Mexico to assess the effects of affordable, sunlight-reflecting cool-roof coatings — an effective home cooling intervention — on health, environmental and economic outcomes for vulnerable populations. The findings will inform global adaptation and policy responses to increasing heat exposure from climate change.