Working with Cofepris, the Ministry of Health, and the CEC, Sonora’s regional health authority (Comisión Estatal de Protección contra Riesgos Sanitarios del Estado de Sonora—Coesprisson) established several objectives with the goal of creating a real-time SyS system for the city of Hermosillo in a 2016 pilot SyS project that would enable timely identification of health impacts due to extreme temperature and evidence-based policy development to reduce mortality and morbidity rates.